"Menopause is a castration event. If I cut your testicles off right now, you would have hot flashes, night sweats, osteoporosis, depression, low libido, erectile dysfunction, metabolic syndrome. Your weight would go up and you would be generally pretty unhappy. It's a big deal when we castrate people. And yet we don't do it for men regularly unless there's a very significant medical reason to do so. And yet every woman over the age of 50, her estrogen goes to essentially zero and that affects bone health. It affects the brain. It affects the heart. It affects sexual health. It affects UTIs."